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KL2 Scholar, Dr. Olarerin-George, collaborates with TL1 Alumna, Dr. Grozhik on Epitranscriptomics Research

Posted Date:
February 3, 2020

News and Congratulations

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Dr. Olarerin-George has been researching Uncovering the role of 8oxoG in neurodegenerative diseases as a CTSC supported K Scholar. His research extends across disciplines and institutions to investigate this complex area(?) of inquiry. He is working in the Jaffrey Lab to conduct transcriptome-wide mapping of 8oxoG under various stimuli and is also partnering with Dr. Flint Beal to seek real world applications for his findings as it pertains to prognostic and therapeutic efforts.  He is also interested in discovering and characterizing other RNA modifications in the transcriptome.

Leveraging a fortuitous collaboration with a CTSC TL1 Alumna,  Anya Grozhik, PhD, Dr. Olarerin-George was able to expand his research. In his own words, they were both “interested in identifying new post-transcriptional modifications in messenger RNA.  Anya’s approach was wet lab based, mine was in silico.  Our projects intersected as we both ended up studying a modification called m1A.  We found that this modification was very rare (unlike what was being reported by other groups), only occurring in a handful of mitochondrial mRNAs.”

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Dr. Anthony Olarerin-George is a fellow in Pharmacology at Weill Cornell Medicine with expertise in Molecular and Computational Biology. His primary mentor is Samie Jaffrey, MD, PhD, Professor of Pharmacology at Weill Cornell Medicine. His secondary mentor is M. Flint Beal, MD, Professor of Neuroscience at Weill Cornell Medicine.

The CTSC KL2 Career Development Core Program supports junior faculty and senior residents and fellows by providing salary support, protected time, advanced degree training, and practical skills necessary to conduct interdisciplinary Clinical Translational Investigation within a team research environment.



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